Evidence & coverage
We don't have access to all testing or clinical information. We show what we have, where it came from, when, what it covers and what it can't tell you.
Six separate layers
01
Clinical research
Studies of an ingredient at a dose, or of the exact finished product. Labelled separately; ingredient studies only count when the declared dose is in range.
02
Label declarations
What the maker says is inside. Declared, not verified.
03
Certifications
Third-party programs (quality, sport screening, vegan, organic). A quality seal is not proof of health benefit.
04
Batch lab tests
Certificates of analysis for a specific batch. They say nothing about other batches.
05
Supplier disclosures
Self-reported manufacturing and sourcing info. Unaudited unless stated.
06
Country status
Product-level regulatory status per country. Unknown status excludes a product from the shortlist.
Order of operations
- 1.Match goals to declared ingredients
- 2.Remove products with safety exclusions for your medicines/conditions
- 3.Remove products not confirmed as permitted in your country
- 4.Rank on ingredient evidence × dose relevance, data completeness, budget and format
- 5.Move thin-data products to a separate limited-data section
- 6.Referral status is never a ranking input
Ingredient research library
Ingredient-level summaries only — not studies of any specific product. Summaries are sample examples; the links open live PubMed searches (randomized trials and systematic reviews) and NIH fact sheets so you can check the original work yourself.
Vitamin D3
Nutrition gaps · moderate
Supplementation raises blood vitamin D levels in people with low intake or sun exposure. Studied: 10–25 µg/day.
Example: NIH ODS Vitamin D fact sheet · 2024-06-01 · Review of trials in adults. Benefit for outcomes beyond status is mixed; demo summary, verify original.
Vitamin D3
Immune support · limited
Some meta-analyses suggest a small effect on respiratory infections, mainly in deficient people. Studied: 10–25 µg/day.
Example: meta-analysis of RCTs · 2021-05-01 · Respiratory infection outcomes. Heterogeneous trials; effect size small.
Vitamin B12
Nutrition gaps · moderate
Reliable way to maintain B12 status on plant-based diets. Studied: ≥25 µg/day.
Example: NIH ODS B12 fact sheet · 2024-03-01 · Status in vegans / older adults. Status, not symptom outcomes.
Vitamin B12
Medication-related concerns · limited
Long-term metformin use is associated with lower B12; monitoring is often advised. Studied: varies.
Example: clinical guideline summary · 2022-01-01 · People on metformin. Testing via clinician preferred over self-supplementing.
Omega-3 (EPA+DHA)
Heart & metabolic wellness · limited
Lowers triglycerides at higher doses; broader cardiovascular outcomes inconsistent. Studied: 1–4 g/day.
Example: Cochrane review · 2020-02-01 · Cardiovascular outcomes. Large trials disagree; prescription-strength doses differ from retail.
Omega-3 (EPA+DHA)
Nutrition gaps · moderate
Raises omega-3 index in people who eat little oily fish. Studied: 250–500 mg/day.
Example: EFSA opinion · 2012-07-01 · Status / intake adequacy. Status marker, not disease outcome.
Omega-3 (EPA+DHA)
Cognitive health & focus · insufficient
Trials in healthy adults have not shown consistent cognitive benefit. Studied: ≥500 mg/day.
Example: systematic review · 2019-01-01 · Healthy adults. Short trials, mixed outcome measures.
Magnesium glycinate
Sleep, stress & mood · limited
Small trials, mostly in older adults or low-magnesium groups, suggest modest sleep improvements. Studied: 200–400 mg/day elemental.
Example: systematic review · 2021-04-01 · Older adults with insomnia. Few, small trials; low certainty.
Melatonin
Sleep, stress & mood · moderate
Modestly shortens time to fall asleep; useful for jet lag. Studied: 0.5–5 mg.
Example: meta-analysis · 2022-01-01 · Adults with sleep onset issues. Prescription-only in some countries (e.g. UK).
Creatine monohydrate
Sport, strength & recovery · moderate
Consistently improves high-intensity performance and lean mass with training. Studied: 3–5 g/day.
Example: ISSN position stand · 2017-06-01 · Training adults. Position stands are expert consensus; not finished-product data.
Whey protein
Sport, strength & recovery · moderate
Supports muscle protein synthesis when total protein intake is otherwise low. Studied: 20–40 g/serving.
Example: meta-analysis · 2018-03-01 · Resistance-training adults. Benefit depends on overall diet.
Psyllium husk
Gut & digestive health · moderate
Improves stool regularity; soluble fiber. Studied: 5–10 g/day.
Example: gastroenterology review · 2019-01-01 · Chronic constipation. Can interact with timing of medicines.
Psyllium husk
Heart & metabolic wellness · moderate
Modestly lowers LDL cholesterol. Studied: ~10 g/day.
Example: meta-analysis · 2018-01-01 · Adults with mild hypercholesterolaemia. Effect modest; not a replacement for treatment.
Lactobacillus rhamnosus GG
Gut & digestive health · limited
Strain-specific evidence, mostly for antibiotic-associated diarrhoea. Studied: ≥10 billion CFU.
Example: guideline review · 2020-06-01 · Strain-specific; antibiotic users. Probiotic effects do not transfer between strains.
Zinc
Immune support · limited
Lozenges started early may shorten colds slightly. Studied: ≥75 mg/day as lozenges, short term.
Example: Cochrane review · 2015-01-01 · Common cold. Formulation matters; long-term high doses cause copper deficiency.
Iron (bisglycinate)
Energy & fatigue · limited
Helps fatigue only when iron is actually low. Studied: 14–60 mg/day.
Example: RCT in iron-deficient non-anaemic women · 2012-01-01 · Iron-deficient adults. Not appropriate without knowing iron status.
Folic acid
Life-stage, reproductive & sexual wellness · moderate
Before and in early pregnancy, reduces neural tube defect risk. Studied: 400 µg/day.
Example: WHO recommendation · 2016-01-01 · Women planning pregnancy. Specific clinical guidance should come from a clinician.
Collagen peptides
Skin, hair & nails · limited
Some industry-funded trials report skin elasticity changes. Studied: 2.5–10 g/day.
Example: meta-analysis · 2021-01-01 · Mostly women, skin outcomes. Many trials industry-funded; high risk of bias.
Biotin
Skin, hair & nails · insufficient
No good evidence for hair/nails in people without deficiency. Studied: n/a.
Example: dermatology review · 2017-01-01 · Hair/nail outcomes. Can interfere with lab tests (e.g. thyroid, troponin).
Vitamin B12
Energy & fatigue · limited
Corrects fatigue linked to low B12; little effect on energy when levels are already adequate. Studied: ≥25 µg/day.
Example: systematic review · 2020-01-01 · People with low B12 vs adequate B12. Benefit seen mainly in deficiency; testing via a clinician is preferable.
Vitamin C
Immune support · limited
Regular use slightly shortens colds in some groups; starting after symptoms begin shows little effect. Studied: 200 mg–1 g/day.
Example: Cochrane review · 2013-01-01 · Common cold prevention/treatment. Small average effect; larger benefit mainly in people under heavy physical stress.
Ashwagandha
Sleep, stress & mood · limited
Small trials report modest reductions in self-reported stress and improved sleep quality. Studied: 250–600 mg/day extract.
Example: systematic review · 2021-03-01 · Adults with stress or sleep complaints. Short, small trials; extract type varies; rare liver injury reports.
Multivitamin (broad)
General wellbeing & healthy aging · limited
Large trials show mixed results; may help those with poor diets. Studied: ~100% NRV.
Example: USPSTF review · 2022-06-01 · General adult population. Not shown to prevent chronic disease in well-nourished adults.
Country regulatory matrix (ingredients)
How each pilot regulator generally treats a few ingredients that are handled very differently between countries. Medicine-only entries, and doses above a stated limit, remove a product before ranking. This is an ingredient-level position, not a product register lookup. Entries are compiled from public regulator positions and marked "needs verification" until a person has checked them against the linked source. No entry means unknown, not allowed.
Melatonin
Sold as a dietary supplement; the FDA does not pre-approve supplements, so label amounts are the maker's declaration.
US FDA — Dietary supplements (DSHEA framework) ↗ · compiled 2026-10-10 · needs verification
Treated as a prescription-only medicine; not lawfully sold as an over-the-counter food supplement.
UK MHRA — Medicines regulation ↗ · compiled 2026-10-10 · needs verification
Food supplements are tolerated only at low daily amounts; higher amounts are generally treated as medicinal products. Thresholds are applied differently by state authorities, so we use a conservative 1 mg/day.
Germany BVL — Food supplements ↗ · compiled 2026-10-10 · needs verification
Generally a prescription (Schedule 4) medicine, with narrow exceptions; not a general-sale supplement.
Australia TGA — Complementary medicines & scheduling ↗ · compiled 2026-10-10 · needs verification
Vitamin D3
Sold as a supplement. The NIH tolerable upper intake for adults is 100 µg (4,000 IU) a day from all sources; higher amounts are usually clinician-directed.
US FDA — Dietary supplements (DSHEA framework) ↗ · compiled 2026-10-10 · needs verification
Sold as a food supplement. UK guidance treats up to 100 µg (4,000 IU) a day as a safe upper level for adults.
UK FSA — Food supplements guidance ↗ · compiled 2026-10-10 · needs verification
The BfR recommends a maximum of 20 µg per daily dose in food supplements; higher-dose products are commonly classed as medicinal products.
Germany BfR — Risk assessment of supplements ↗ · compiled 2026-10-10 · needs verification
Available as a listed complementary medicine. Higher-strength products may fall under scheduling (pharmacy/prescription) controls.
Australia TGA — Complementary medicines & scheduling ↗ · compiled 2026-10-10 · needs verification
Ashwagandha
Sold as a dietary supplement. Rare liver-injury case reports exist; the FDA does not pre-approve it.
US FDA — Dietary supplements (DSHEA framework) ↗ · compiled 2026-10-10 · needs verification
Sold as a food supplement; regulators advise caution because of rare liver-injury reports.
UK FSA — Food supplements guidance ↗ · compiled 2026-10-10 · needs verification
Marketed as a food supplement, but German risk assessors have flagged safety questions; some EU countries restrict it.
Germany BfR — Risk assessment of supplements ↗ · compiled 2026-10-10 · needs verification
Available as a listed complementary medicine, with required label warnings about liver injury.
Australia TGA — Complementary medicines & scheduling ↗ · compiled 2026-10-10 · needs verification
Kava
Sold as a dietary supplement; the FDA has issued a consumer advisory about rare liver injury.
US FDA — Dietary supplements (DSHEA framework) ↗ · compiled 2026-10-10 · needs verification
Kava for internal use is prohibited from sale or supply under a UK prohibition order.
UK MHRA — Medicines regulation ↗ · compiled 2026-10-10 · needs verification
Kava products are tightly restricted after past liver-safety concerns; not accepted as an ordinary food supplement.
Germany BfR — Risk assessment of supplements ↗ · compiled 2026-10-10 · needs verification
Kava is tightly controlled (limited forms and quantities); not a general-sale supplement.
Australia TGA — Complementary medicines & scheduling ↗ · compiled 2026-10-10 · needs verification
Market coverage
Pilot markets are where we intend to validate the flow first. All status data today is sample data.
| Market | Coverage | Status source | Note |
|---|---|---|---|
| United States | Pilot (sample) | FDA (DSHEA) | Demo status data only. Supplements are not pre-approved in the US. |
| United Kingdom | Pilot (sample) | FSA / MHRA | Demo status data only. |
| Germany | Pilot (sample) | BVL (EU food supplement notification) | Demo status data only. |
| Australia | Pilot (sample) | TGA (ARTG listing) | Demo status data only. |
| Canada | Gap | — | Not covered yet: no retailer feed or NPN status source configured. |
| India | Gap | — | Not covered yet. |
| Brazil | Gap | — | Not covered yet. |
| Japan | Gap | — | Not covered yet. |
| Other country | Gap | — | Not covered yet. |
Data sources
| Source | Type | Last snapshot | Live? |
|---|---|---|---|
| RetailerA | Retailer feed | 2026-10-02 | Not configured |
| RetailerB | Retailer feed | 2026-10-05 | Not configured |
| RetailerC | Retailer feed | 2026-09-30 | Not configured |
| NIH DSLD (US supplement labels) | Label lookup | On request | Live, display-only |
| Open Food Facts (international listings) | Community-edited listing lookup | On request | Live, display-only |
| Clinical literature index | Reference | — | Not configured |
| Regulator registers | Reference | — | Not configured |
| Lab CoA repository | Reference | — | Not configured |
| Certifier directories | Reference | — | Not configured |